2 (8 ounce) packages cream cheese, softened
1 (16 ounce) package shredded Italian cheese blend
1 cup mayonnaise
1 tablespoon onion powder
1 tablespoon garlic powder
1 (18 ounce) loaf round bread loaf, hollowed to make a bowl
Preheat oven to 350 degrees F (175 degrees C).
Stir cream cheese, Italian cheese blend, mayonnaise, onion powder, and garlic powder together in a bowl; scoop into bread bowl.
Bake in preheated oven until heated through, 90 minutes to 2 hours.